An Introduction to Gerontology by Ian Stuart-Hamilton

By Ian Stuart-Hamilton

With the world's inhabitants getting more and more older, there hasn't ever been a extra urgent desire for the learn of previous age and growing old. An advent to Gerontology presents a wide-ranging creation to this crucial subject. by means of assuming no past specialist wisdom and heading off jargon, this booklet will consultant scholars via the entire major matters in gerontology, overlaying either conventional components, comparable to organic and social getting older, in addition to extra modern parts, akin to know-how, the humanities, sexuality and schooling of older adults. An advent to Gerontology is written by means of a crew of foreign authors with multidisciplinary backgrounds who draw facts from a number of varied views and traditions.

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Marmot, M. (2001) Inequalities in health, New England Journal of Medicine, 345, 134–6. Marmot, M. and Feeney, A. (1997) General explanations for social inequalities in health, IARC Scientific Publications, 138, 207–28. B. (1952) An unsolved problem of biology. K. Lewis. B. et al. (2004) Development and validation of a geriatric knowledge test for medical students, Journal of the American Geriatrics Society, 52, 983–8. Mullan, P. (2002) The imaginary time bomb: why an ageing population is not a social problem.

Furthermore, a deleterious mutation that is harmful or even lethal at age 5 will not be selected against because few if any animals will ever reach such age, allowing late-acting hazardous alleles to persist in the population. This theory became known as the mutation accumulation theory (Hamilton, 1966; Kirkwood and Austad, 2000; Rose, 1991). Shortly afterwards, a complementary theory was developed by George Williams (1957). This argued that a gene that increases the chances of the survival of a mouse to reproductive age will be favoured even if the same gene produces lethal effects at age 5.

Much research has focused on RS, telomeres and telomerase. At present, their relevance to the ageing process is unclear, though there is abundant evidence that RS and telomere shortening are anti-cancer mechanisms (Campisi, 2005; de Magalh˜aes, 2004). , 2002). , 2008). , 1998). 12 on Thu Oct 11 11:23:13 BST 2012. , 2005). , 2002). Programmed theories of ageing At the root of programmed theories of ageing is the idea that ageing is not a result of random or stochastic processes but rather it is driven by genetically regulated processes or predetermined mechanisms, even if these can be influenced to some degree by environmental factors and ultimately cause certain forms of damage.

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