By Ronald DeMatteo
Even if you are a newly clinically determined GI Stromal sufferer, a survivor, or a chum or relative of both, this publication deals support. the single textual content to supply the doctor's and patient's perspectives, a hundred Questions & solutions approximately Gastrointestinal Stromal Tumors (GIST) provides authoritative, sensible solutions on your questions about treatments, post-treatment caliber of existence, resources of help, and masses extra. This booklet is a useful source for someone dealing with the actual and emotional turmoil of this scary illness.
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Extra resources for 100 Questions & Answers About Gastrointestinal Stromal Tumor(GIST)
Many cancer cells promote this growth of tumor-feeding blood vessels by releasing a protein called vascular endothelial growth factor (VEGF). This VEGF stimulates the growth of the endothelial cells required to form capillaries. VEGF released from the GIST cells combines with a receptor protein on the surface of the endothelial cells and thereby activates growth signals inside of the endothelial cell. Anti-angiogenic therapies are supposed to interfere with this abnormal angiogenesis. A tumor cannot grow any larger without new blood vessels.
GISTs tend to occur in patients who are between 40 and 80 years old. Slightly more men than women have GISTs. The disease rarely occurs in children or young adolescents. The distribution of GISTs by race is uncertain, as large epidemiology studies have not yet been performed. 13. Did something in my environment cause my GIST? No environ mental factors appear to be associated with GIST. No environmental factors appear to be associated with GISTs. Because of the infrequency of the disease, however, there has not been any formal study of risk factors for GISTs.
A GIST can also be discovered incidentally on a radiologic test such as a CT scan or an MRI or during an abdominal operation that is performed for some other reason. An endoscopy or colonoscopy may also identify an unsuspected GIST. Fatigue, unintentional weight loss, a change in bowel habits, decreased appetite, and chronic, low-grade fevers may also be evident. These symptoms are not specific for GIST, however, and may occur with other tumors or benign conditions, such as ulcers, diverticulitis, or inflammatory bowel disease.